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BMCBI
2008
163views more  BMCBI 2008»
15 years 6 months ago
Nuclear staining and relative distance for quantifying epidermal differentiation in biomarker expression profiling
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
Thora Pommerencke, Thorsten Steinberg, Hartmut Dic...
BMCBI
2008
115views more  BMCBI 2008»
15 years 6 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
BMCBI
2008
111views more  BMCBI 2008»
15 years 6 months ago
A perl package and an alignment tool for phylogenetic networks
Background: Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of evolutionary events acting at the population level, like recombin...
Gabriel Cardona, Francesc Rosselló, Gabriel...
BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Determining gene expression on a single pair of microarrays
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
Robert W. Reid, Anthony A. Fodor
BMCBI
2008
126views more  BMCBI 2008»
15 years 6 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
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