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166
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BMCBI
2010
15 years 6 months ago
2010
Background: Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip, generate large numbers of experimentally...
186
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BMCBI
2010
15 years 6 months ago
2010
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
169
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BMCBI
2008
15 years 6 months ago
2008
Background: Computational biology is often associated with genetic or genomic studies only. However, thanks to the increase of computational resources, computational models are ap...
186
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BMCBI
2007
15 years 6 months ago
2007
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
185
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BMCBI
2008
15 years 6 months ago
2008
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...