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BMCBI
2008
121views more  BMCBI 2008»
15 years 6 months ago
Modularization of biochemical networks based on classification of Petri net t-invariants
Background: Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from ...
Eva Grafahrend-Belau, Falk Schreiber, Monika Heine...
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Extended morphological processing: a practical method for automatic spot detection of biological markers from microscopic images
Background: A reliable extraction technique for resolving multiple spots in light or electron microscopic images is essential in investigations of the spatial distribution and dyn...
Yoshitaka Kimori, Norio Baba, Nobuhiro Morone
161
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BMCBI
2010
123views more  BMCBI 2010»
15 years 6 months ago
An improved classification of G-protein-coupled receptors using sequence-derived features
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
BMCBI
2010
139views more  BMCBI 2010»
15 years 6 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2008
169views more  BMCBI 2008»
15 years 6 months ago
MausDB: An open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects
Background: Large-scale, comprehensive and standardized high-throughput mouse phenotyping has been established as a tool of functional genome research by the German Mouse Clinic a...
Holger Maier, Christoph Lengger, Bruno Simic, Helm...
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