42507 search results - page 8181 / 8502 » On the analysis of |
198
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BMCBI
2010
15 years 7 months ago
2010
Background: Traditional algorithms for hidden Markov model decoding seek to maximize either the probability of a state path or the number of positions of a sequence assigned to th...
190
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BMCBI
2007
15 years 7 months ago
2007
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
219
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BMCBI
2007
15 years 7 months ago
2007
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...
166
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BMCBI
2010
15 years 7 months ago
2010
Background: There is a vast need to find clinically applicable protein biomarkers as support in cancer diagnosis and tumour classification. In proteomics research, a number of met...
181
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BMCBI
2010
15 years 7 months ago
2010
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...