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BMCBI
2006
109views more  BMCBI 2006»
15 years 7 months ago
An integrated system for genetic analysis
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...
BMCBI
2006
119views more  BMCBI 2006»
15 years 7 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
BMCBI
2006
153views more  BMCBI 2006»
15 years 7 months ago
2DDB - a bioinformatics solution for analysis of quantitative proteomics data
Background: We present 2DDB, a bioinformatics solution for storage, integration and analysis of quantitative proteomics data. As the data complexity and the rate with which it is ...
Lars Malmström, György Marko-Varga, Guni...
BMCBI
2006
154views more  BMCBI 2006»
15 years 7 months ago
Analysis with respect to instrumental variables for the exploration of microarray data structures
Background: Evaluating the importance of the different sources of variations is essential in microarray data experiments. Complex experimental designs generally include various fa...
Florent Baty, Michaël Facompré, Jan Wi...
BMCBI
2006
161views more  BMCBI 2006»
15 years 7 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang