9871 search results - page 1829 / 1975 » On the Structure of Low Sets |
145
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BMCBI
2010
15 years 6 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
173
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BMCBI
2010
15 years 6 months ago
2010
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
155
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BMCBI
2008
15 years 6 months ago
2008
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
155
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BMCBI
2010
15 years 6 months ago
2010
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
199
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BMCBI
2008
15 years 6 months ago
2008
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...