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» On the Optimality of Spiral Search
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BMCBI
2010
137views more  BMCBI 2010»
15 years 6 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
BMCBI
2006
194views more  BMCBI 2006»
15 years 6 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
CPHYSICS
2006
127views more  CPHYSICS 2006»
15 years 6 months ago
GenAnneal: Genetically modified Simulated Annealing
A modification of the standard Simulated Annealing (SA) algorithm is presented for finding the global minimum of a continuous multidimensional, multimodal function. We report resu...
Ioannis G. Tsoulos, Isaac E. Lagaris
CPHYSICS
2006
182views more  CPHYSICS 2006»
15 years 6 months ago
MinFinder: Locating all the local minima of a function
A new stochastic clustering algorithm is introduced that aims to locate all the local minima of a multidimensional continuous and differentiable function inside a bounded domain. ...
Ioannis G. Tsoulos, Isaac E. Lagaris
EAAI
2006
189views more  EAAI 2006»
15 years 6 months ago
Evolutionary algorithms for VLSI multi-objective netlist partitioning
The problem of partitioning appears in several areas ranging from VLSI, parallel programming, to molecular biology. The interest in finding an optimal partition especially in VLSI ...
Sadiq M. Sait, Aiman H. El-Maleh, Raslan H. Al-Aba...