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BMCBI
2007
135views more  BMCBI 2007»
15 years 6 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
BMCBI
2008
100views more  BMCBI 2008»
15 years 6 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
BMCBI
2006
134views more  BMCBI 2006»
15 years 6 months ago
An approach for clustering gene expression data with error information
Background: Clustering of gene expression patterns is a well-studied technique for elucidating trends across large numbers of transcripts and for identifying likely co-regulated g...
Brian Tjaden
BMCBI
2006
242views more  BMCBI 2006»
15 years 6 months ago
Predicting residue-wise contact orders in proteins by support vector regression
Background: The residue-wise contact order (RWCO) describes the sequence separations between the residues of interest and its contacting residues in a protein sequence. It is a ne...
Jiangning Song, Kevin Burrage
BMCBI
2007
78views more  BMCBI 2007»
15 years 6 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga