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» On the Complexity of Real Functions
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BMCBI
2005
118views more  BMCBI 2005»
15 years 6 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
COCO
2009
Springer
106views Algorithms» more  COCO 2009»
16 years 1 months ago
Improved Approximation of Linear Threshold Functions
We prove two main results on how arbitrary linear threshold functions f(x) = sign(w · x − θ) over the n-dimensional Boolean hypercube can be approximated by simple threshold f...
Ilias Diakonikolas, Rocco A. Servedio
ICFP
2000
ACM
15 years 11 months ago
Functional programming in C++
This paper describes FC++: a rich library supporting functional programming in C++. Prior approaches to encoding higher order functions in C++ have suffered with respect to polymo...
Brian McNamara, Yannis Smaragdakis
BMCBI
2005
112views more  BMCBI 2005»
15 years 6 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...
KDD
2003
ACM
130views Data Mining» more  KDD 2003»
16 years 7 months ago
Towards systematic design of distance functions for data mining applications
Distance function computation is a key subtask in many data mining algorithms and applications. The most effective form of the distance function can only be expressed in the conte...
Charu C. Aggarwal