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172
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BMCBI
2006
15 years 7 months ago
2006
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
173
Voted
BMCBI
2005
15 years 6 months ago
2005
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
197
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MST
2007
15 years 6 months ago
2007
In 1996, Khanna and Motwani [KM96] proposed three logic-based optimization problems constrained by planar structure, and offered the hypothesis that these putatively fundamental ...
196
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KDD
2009
ACM
16 years 1 months ago
2009
ACM
To discover patterns in historical data, climate scientists have applied various clustering methods with the goal of identifying regions that share some common climatological beha...
174
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FOCS
2007
IEEE
16 years 1 months ago
2007
IEEE
We propose a proof-theoretic approach for gaining evidence that certain parameterized problems are not fixedparameter tractable. We consider proofs that witness that a given prop...