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BMCBI
2010
163views more  BMCBI 2010»
15 years 6 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
BMCBI
2010
136views more  BMCBI 2010»
15 years 6 months ago
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Ma...
BMCBI
2010
189views more  BMCBI 2010»
15 years 6 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
BMCBI
2007
219views more  BMCBI 2007»
15 years 6 months ago
MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments
Background: Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many effor...
Jean-Baptiste Veyrieras, Bruno Goffinet, Alain Cha...
BMCBI
2008
115views more  BMCBI 2008»
15 years 6 months ago
BioGraphE: high-performance bionetwork analysis using the Biological Graph Environment
Background: Graphs and networks are common analysis representations for biological systems. Many traditional graph algorithms such as k-clique, k-coloring, and subgraph matching h...
George Chin Jr., Daniel G. Chavarría-Mirand...