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BMCBI
2007
127views more  BMCBI 2007»
15 years 6 months ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
BMCBI
2008
113views more  BMCBI 2008»
15 years 6 months ago
Investigating selection on viruses: a statistical alignment approach
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...
BMCBI
2008
138views more  BMCBI 2008»
15 years 6 months ago
Information transfer in signaling pathways: A study using coupled simulated and experimental data
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown. Since quite divers...
Jürgen Pahle, Anne K. Green, C. Jane Dixon, U...
BMCBI
2010
65views more  BMCBI 2010»
15 years 6 months ago
VIPR: A probabilistic algorithm for analysis of microbial detection microarrays
Background: All infectious disease oriented clinical diagnostic assays in use today focus on detecting the presence of a single, well defined target agent or a set of agents. In r...
Adam F. Allred, Guang Wu, Tuya Wulan, Kael F. Fisc...
BMCBI
2007
97views more  BMCBI 2007»
15 years 6 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
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