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BMCBI
2010
150views more  BMCBI 2010»
15 years 6 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2010
137views more  BMCBI 2010»
15 years 6 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
BMCBI
2010
117views more  BMCBI 2010»
15 years 6 months ago
New decoding algorithms for Hidden Markov Models using distance measures on labellings
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
Daniel G. Brown 0001, Jakub Truszkowski
CORR
2006
Springer
146views Education» more  CORR 2006»
15 years 6 months ago
Approximation Algorithms for Multi-Criteria Traveling Salesman Problems
In multi-criteria optimization, several objective functions are to be optimized. Since the different objective functions are usually in conflict with each other, one cannot conside...
Bodo Manthey, L. Shankar Ram
CN
2010
91views more  CN 2010»
15 years 4 months ago
ILP formulations for non-simple p-cycle and p-trail design in WDM mesh networks
Conventional simple p-cycle (Preconfigured Protection Cycle) concept allows fast and capacity-efficient span protection in WDM mesh networks. Unlike simple p-cycle, non-simple p-cy...
Bin Wu, Kwan L. Yeung, Pin-Han Ho