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BMCBI
2007
107views more  BMCBI 2007»
15 years 6 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...
SIAMIS
2008
174views more  SIAMIS 2008»
15 years 6 months ago
Efficient Reconstruction of Piecewise Constant Images Using Nonsmooth Nonconvex Minimization
We consider the restoration of piecewise constant images where the number of the regions and their values are not fixed in advance, with a good difference of piecewise constant val...
Mila Nikolova, Michael K. Ng, Shuqin Zhang, Wai-Ki...
BMCBI
2005
189views more  BMCBI 2005»
15 years 6 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
JCB
2007
130views more  JCB 2007»
15 years 6 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
TSE
2008
165views more  TSE 2008»
15 years 6 months ago
A Systematic Study of Failure Proximity
Software end users are the best testers, who keep revealing bugs in software that has undergone rigorous in-house testing. In order to leverage their testing efforts, failure repor...
Chao Liu 0001, Xiangyu Zhang, Jiawei Han