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220
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BMCBI
2010
15 years 7 months ago
2010
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
199
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BMCBI
2010
15 years 7 months ago
2010
Background: High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these ...
173
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BMCBI
2008
15 years 7 months ago
2008
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
244
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BMCBI
2008
15 years 7 months ago
2008
Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
194
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BMCBI
2008
15 years 7 months ago
2008
Background: Present-day `-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) a...