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BMCBI
2010
160views more  BMCBI 2010»
15 years 6 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2007
149views more  BMCBI 2007»
15 years 6 months ago
Novel and simple transformation algorithm for combining microarray data sets
Background: With microarray technology, variability in experimental environments such as RNA sources, microarray production, or the use of different platforms, can cause bias. Suc...
Ki-Yeol Kim, Dong Hyuk Ki, Ha Jin Jeong, Hei-Cheul...
BMCBI
2008
128views more  BMCBI 2008»
15 years 6 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2008
105views more  BMCBI 2008»
15 years 6 months ago
Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania
Background: Leishmania and other members of the Trypanosomatidae family diverged early on in eukaryotic evolution and consequently display unique cellular properties. Their appare...
Martin Smith, Mathieu Blanchette, Barbara Papadopo...
CE
2008
128views more  CE 2008»
15 years 6 months ago
Beyond threaded discussion: Representational guidance in asynchronous collaborative learning environments
Although most online learning environments are predominately text based, researchers have argued that representational support for the conceptual structure of a problem would addr...
Daniel D. Suthers, Ravi K. Vatrapu, Richard Medina...