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BMCBI
2010
167views more  BMCBI 2010»
15 years 6 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
BMCBI
2010
153views more  BMCBI 2010»
15 years 6 months ago
Automatic symptom name normalization in clinical records of traditional Chinese medicine
Background: In recent years, Data Mining technology has been applied more than ever before in the field of traditional Chinese medicine (TCM) to discover regularities from the exp...
Yaqiang Wang, Zhonghua Yu, Yongguang Jiang, Kaikuo...
BMCBI
2010
151views more  BMCBI 2010»
15 years 6 months ago
Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
Zhanchao Li, Xuan Zhou, Zong Dai, Xiaoyong Zou
BMCBI
2010
72views more  BMCBI 2010»
15 years 6 months ago
Phylogenetic representativeness: a new method for evaluating taxon sampling in evolutionary studies
Background: Taxon sampling is a major concern in phylogenetic studies. Incomplete, biased, or improper taxon sampling can lead to misleading results in reconstructing evolutionary...
Federico Plazzi, Ronald R. Ferrucci, Marco Passamo...
BMCBI
2007
130views more  BMCBI 2007»
15 years 6 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan