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» On Computing Functions with Uncertainty
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174
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BMCBI
2007
97views more  BMCBI 2007»
15 years 7 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
197
Voted
BMCBI
2006
156views more  BMCBI 2006»
15 years 7 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...
189
Voted
BMCBI
2006
129views more  BMCBI 2006»
15 years 7 months ago
Functional clustering of yeast proteins from the protein-protein interaction network
Background: The abundant data available for protein interaction networks have not yet been fully understood. New types of analyses are needed to reveal organizational principles o...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
189
Voted
BMCBI
2007
116views more  BMCBI 2007»
15 years 6 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
207
Voted
BMCBI
2002
110views more  BMCBI 2002»
15 years 6 months ago
Identifying functional relationships among human genes by systematic analysis of biological literature
Background: The availability of biomedical literature in electronic format has made it possible to implement automatic text processing methods to expose implicit relationships amo...
Yong-Chuan Tao, Rudolph L. Leibel