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» On Computing Functions with Uncertainty
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BMCBI
2006
102views more  BMCBI 2006»
15 years 6 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
BCB
2010
126views Bioinformatics» more  BCB 2010»
15 years 1 months ago
Functional similarities of reaction sets in metabolic pathways
Analyzing metabolic pathways by means of their steady states has proven to be accurate and efficient for practical purposes. The models such as elementary flux modes (EFMs) and ex...
Ferhat Ay, Tamer Kahveci
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
16 years 1 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
DAC
1994
ACM
15 years 10 months ago
Optimum Functional Decomposition Using Encoding
In this paper, we revisit the classical problem of functional decomposition [1, 2] that arises so often in logic synthesis. One basic problem that has remained largely unaddressed...
Rajeev Murgai, Robert K. Brayton, Alberto L. Sangi...
CPHYSICS
2006
204views more  CPHYSICS 2006»
15 years 6 months ago
Genetically controlled random search: a global optimization method for continuous multidimensional functions
A new stochastic method for locating the global minimum of a multidimensional function inside a rectangular hyperbox is presented. A sampling technique is employed that makes use ...
Ioannis G. Tsoulos, Isaac E. Lagaris