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BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
CGF
2008
141views more  CGF 2008»
15 years 6 months ago
Interactive Visualization of Multimodal Volume Data for Neurosurgical Tumor Treatment
Teaser Figure: Left: Brain, visualized using silhouettes, the lesion's spatial depth is displayed using a ring. Center: Combined rendering of brain tissue, skull and fiber tr...
Christian Rieder, Felix Ritter, Matthias Raspe, He...
BMCBI
2005
115views more  BMCBI 2005»
15 years 6 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
15 years 4 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
STOC
2009
ACM
163views Algorithms» more  STOC 2009»
16 years 7 months ago
Non-monotone submodular maximization under matroid and knapsack constraints
Submodular function maximization is a central problem in combinatorial optimization, generalizing many important problems including Max Cut in directed/undirected graphs and in hy...
Jon Lee, Vahab S. Mirrokni, Viswanath Nagarajan, M...