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BMCBI
2005
114views more  BMCBI 2005»
15 years 7 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...
NAR
2011
357views Computer Vision» more  NAR 2011»
15 years 2 months ago
miRGator v2.0 : an integrated system for functional investigation of microRNAs
miRGator is an integrated database of microRNA (miRNA)-associated gene expression, target prediction, disease association and genomic annotation, which aims to facilitate function...
Sooyoung Cho, Yukyung Jun, Sanghyun Lee, Hyung-Seo...
NAR
2011
257views Computer Vision» more  NAR 2011»
14 years 10 months ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
FOCS
2009
IEEE
16 years 2 months ago
Instance-Optimal Geometric Algorithms
We prove the existence of an algorithm A for computing 2-d or 3-d convex hulls that is optimal for every point set in the following sense: for every set S of n points and for ever...
Peyman Afshani, Jérémy Barbay, Timot...
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
15 years 7 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...