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NAR
2011
225views Computer Vision» more  NAR 2011»
14 years 10 months ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...
SIGMOD
2009
ACM
140views Database» more  SIGMOD 2009»
16 years 7 months ago
Estimating the confidence of conditional functional dependencies
Conditional functional dependencies (CFDs) have recently been proposed as extensions of classical functional dependencies that apply to a certain subset of the relation, as specif...
Graham Cormode, Lukasz Golab, Flip Korn, Andrew Mc...
BMCBI
2006
102views more  BMCBI 2006»
15 years 7 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
BCB
2010
126views Bioinformatics» more  BCB 2010»
15 years 2 months ago
Functional similarities of reaction sets in metabolic pathways
Analyzing metabolic pathways by means of their steady states has proven to be accurate and efficient for practical purposes. The models such as elementary flux modes (EFMs) and ex...
Ferhat Ay, Tamer Kahveci
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
16 years 1 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...