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» On Compressibility of Protein Sequences
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BMCBI
2006
92views more  BMCBI 2006»
15 years 6 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
TaxMan: a taxonomic database manager
Background: Phylogenetic analysis of large, multiple-gene datasets, assembled from public sequence databases, is rapidly becoming a popular way to approach difficult phylogenetic ...
Martin Jones, Mark Blaxter
IJDMB
2008
128views more  IJDMB 2008»
15 years 6 months ago
Protein homology detection with biologically inspired features and interpretable statistical models
: Computational classification of proteins using methods such as string kernels and Fisher-SVM has demonstrated great success. However, the resulting models do not offer an immedia...
Pai-Hsi Huang, Vladimir Pavlovic
NAR
2008
119views more  NAR 2008»
15 years 6 months ago
MALISAM: a database of structurally analogous motifs in proteins
MALISAM (manual alignments for structurally analogous motifs) represents the first database containing pairs of structural analogs and their alignments. To find reliable analogs, ...
Hua Cheng, Bong-Hyun Kim, Nick V. Grishin
BMCBI
2004
102views more  BMCBI 2004»
15 years 6 months ago
No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions
Background: Alternative splicing is an efficient mechanism for increasing the variety of functions fulfilled by proteins in a living cell. It has been previously demonstrated that...
Marc N. Offman, Ramil N. Nurtdinov, Mikhail S. Gel...