When aligning biological sequences, the choice of parameter values for the alignment scoring function is critical. Small changes in gap penalties, for example, can yield radically ...
Multiple sequence alignment has been a useful methodin the study of molecular evolution and sequence-structure relationships. This paper presents a newmethodfor multiple sequence ...
De novo Sequencing of peptides is a challenging task in proteome research. While there exist reliable DNA-sequencing methods, the highthroughput de novo sequencing of proteins by ...
Bernd Fischer, Volker Roth, Joachim M. Buhmann, Jo...
Background: Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires specifically-designed crosslinking reagents...
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...