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» On Bounded Queries and Approximation
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BMCBI
2010
80views more  BMCBI 2010»
15 years 6 months ago
Sampling the conformation of protein surface residues for flexible protein docking
Background: The problem of determining the physical conformation of a protein dimer, given the structures of the two interacting proteins in their unbound state, is a difficult on...
Patricia Francis-Lyon, Shengyin Gu, Joel Hass, Nin...
ICALP
2011
Springer
14 years 10 months ago
Vertex Cover in Graphs with Locally Few Colors
In [13], Erd˝os et al. defined the local chromatic number of a graph as the minimum number of colors that must appear within distance 1 of a vertex. For any ∆ ≥ 2, there are ...
Fabian Kuhn, Monaldo Mastrolilli
DATESO
2007
157views Database» more  DATESO 2007»
15 years 8 months ago
Index-Based Approach to Similarity Search in Protein and Nucleotide Databases
When searching databases of nucleotide or protein sequences, finding a local alignment of two sequences is one of the main tasks. Since the sizes of available databases grow const...
David Hoksza, Tomás Skopal
SIGMOD
2004
ACM
126views Database» more  SIGMOD 2004»
16 years 6 months ago
Indexing Spatio-Temporal Trajectories with Chebyshev Polynomials
In this paper, we attempt to approximate and index a ddimensional (d 1) spatio-temporal trajectory with a low order continuous polynomial. There are many possible ways to choose ...
Yuhan Cai, Raymond T. Ng
FOCS
2007
IEEE
16 years 1 months ago
Adaptive Simulated Annealing: A Near-optimal Connection between Sampling and Counting
We present a near-optimal reduction from approximately counting the cardinality of a discrete set to approximately sampling elements of the set. An important application of our wo...
Daniel Stefankovic, Santosh Vempala, Eric Vigoda