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BMCBI
2005
128views more  BMCBI 2005»
15 years 6 months ago
Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process
Background: Biological Mass Spectrometry is used to analyse peptides and proteins. A mass spectrum generates a list of measured mass to charge ratios and intensities of ionised pe...
Witold E. Wolski, Maciej Lalowski, Peter Martus, R...
JCB
2007
146views more  JCB 2007»
15 years 6 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
BMCBI
2004
88views more  BMCBI 2004»
15 years 6 months ago
Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology
Background: Despite the passing of more than a year since the first outbreak of Severe Acute Respiratory Syndrome (SARS), efficient counter-measures are still few and many believe...
Lars Kiemer, Ole Lund, Søren Brunak, Nikola...
BMCBI
2004
134views more  BMCBI 2004»
15 years 6 months ago
Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE)
Background: An important challenge for transcript counting methods such as Serial Analysis of Gene Expression (SAGE), "Digital Northern" or Massively Parallel Signature ...
Ricardo Z. N. Vêncio, Helena Brentani, Diogo...
MOC
2000
105views more  MOC 2000»
15 years 6 months ago
On the iteratively regularized Gauss-Newton method for solving nonlinear ill-posed problems
The iteratively regularized Gauss-Newton method is applied to compute the stable solutions to nonlinear ill-posed problems F (x) = y when the data y is given approximately by y wit...
Jin Qi-nian