4234 search results - page 675 / 847 » OLAP on sequence data |
159
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BMCBI
2008
15 years 6 months ago
2008
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
186
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BMCBI
2008
15 years 6 months ago
2008
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
166
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AMC
2006
15 years 6 months ago
2006
Earlier work by Saha et al. rigorously derived a general probabilistic model for the PCR process that includes as a special case the Velikanov-Kapral model where all nucleotide re...
173
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BMCBI
2006
15 years 6 months ago
2006
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
164
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BMCBI
2006
15 years 6 months ago
2006
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...