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COMPGEOM
2006
ACM
15 years 10 months ago
I/O-efficient batched union-find and its applications to terrain analysis
Despite extensive study over the last four decades and numerous applications, no I/O-efficient algorithm is known for the union-find problem. In this paper we present an I/O-effic...
Pankaj K. Agarwal, Lars Arge, Ke Yi
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
15 years 6 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
BMCBI
2010
110views more  BMCBI 2010»
15 years 6 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
110views more  BMCBI 2008»
15 years 6 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
BMCBI
2007
175views more  BMCBI 2007»
15 years 6 months ago
Apollo2Go: a web service adapter for the Apollo genome viewer to enable distributed genome annotation
Background: Apollo, a genome annotation viewer and editor, has become a widely used genome annotation and visualization tool for distributed genome annotation projects. When using...
Kathrin Klee, Rebecca Ernst, Manuel Spannagl, Klau...