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177
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BMCBI
2005
15 years 6 months ago
2005
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
194
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BMCBI
2005
15 years 6 months ago
2005
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
176
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BMCBI
2005
15 years 6 months ago
2005
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
203
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BMCBI
2005
15 years 6 months ago
2005
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
166
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BMCBI
2005
15 years 6 months ago
2005
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...