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BMCBI
2008
110views more  BMCBI 2008»
15 years 7 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
BMCBI
2006
87views more  BMCBI 2006»
15 years 7 months ago
MathDAMP: a package for differential analysis of metabolite profiles
Background: With the advent of metabolomics as a powerful tool for both functional and biomarker discovery, the identification of specific differences between complex metabolite p...
Richard Baran, Hayataro Kochi, Natsumi Saito, Mako...
SP
2008
IEEE
122views Security Privacy» more  SP 2008»
15 years 6 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...
BMCBI
2005
145views more  BMCBI 2005»
15 years 6 months ago
CAGER: classification analysis of gene expression regulation using multiple information sources
Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
Jianhua Ruan, Weixiong Zhang
BMCBI
2005
98views more  BMCBI 2005»
15 years 6 months ago
InterferenceAnalyzer: Tools for the analysis and simulation of multi-locus genetic data
Background: Good statistical models for analyzing and simulating multilocus recombination data exist but are not accessible to many biologists because their use requires reasonabl...
Lalitha Viswanath, Elizabeth A. Housworth