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BMCBI
2006
120views more  BMCBI 2006»
15 years 7 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
BMCBI
2006
112views more  BMCBI 2006»
15 years 7 months ago
MassSorter: a tool for administrating and analyzing data from mass spectrometry experiments on proteins with known amino acid se
Background: Proteomics is the study of the proteome, and is critical to the understanding of cellular processes. Two central and related tasks of proteomics are protein identifica...
Harald Barsnes, Svein-Ole Mikalsen, Ingvar Eidhamm...
BMCBI
2006
167views more  BMCBI 2006»
15 years 7 months ago
GOurmet: A tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributi
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
Jason M. Doherty, Lynn K. Carmichael, Jason C. Mil...
BMCBI
2006
145views more  BMCBI 2006»
15 years 7 months ago
Querying the public databases for sequences using complex keywords contained in the feature lines
Background: High throughput technologies often require the retrieval of large data sets of sequences. Retrieval of EMBL or GenBank entries using keywords is easy using tools such ...
Olivier Croce, Michaël Lamarre, Richard Chris...
BMCBI
2006
101views more  BMCBI 2006»
15 years 7 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...