6223 search results - page 891 / 1245 » New architectures for a new biology |
196
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BMCBI
2010
15 years 7 months ago
2010
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
170
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BMCBI
2008
15 years 7 months ago
2008
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
180
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BMCBI
2008
15 years 7 months ago
2008
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
234
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BMCBI
2010
15 years 7 months ago
2010
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
197
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BMCBI
2007
15 years 7 months ago
2007
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...