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BIOINFORMATICS
2010
15 years 6 months ago
2010
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
220
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BIOINFORMATICS
2008
15 years 6 months ago
2008
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
175
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BMCBI
2010
15 years 6 months ago
2010
Background: Large genomes contain families of highly similar genes that cannot be individually identified by microarray probes. This limitation is due to thermodynamic restriction...
186
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BMCBI
2010
15 years 6 months ago
2010
Background: Coevolutionary systems like hosts and their parasites are commonly used model systems for evolutionary studies. Inferring the coevolutionary history based on given phy...
163
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BMCBI
2010
15 years 6 months ago
2010
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...