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BMCBI
2008
104views more  BMCBI 2008»
15 years 6 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
BMCBI
2007
151views more  BMCBI 2007»
15 years 6 months ago
Minimus: a fast, lightweight genome assembler
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
Daniel D. Sommer, Arthur L. Delcher, Steven L. Sal...
BMCBI
2007
134views more  BMCBI 2007»
15 years 6 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
BMCBI
2008
120views more  BMCBI 2008»
15 years 6 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
BMCBI
2008
150views more  BMCBI 2008»
15 years 6 months ago
13C labeling experiments at metabolic nonstationary conditions: An exploratory study
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
Sebastian Aljoscha Wahl, Katharina Nöh, Wolfg...
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