16504 search results - page 3242 / 3301 » New Problems, New Solutions |
151
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BMCBI
2008
15 years 6 months ago
2008
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
165
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BMCBI
2008
15 years 6 months ago
2008
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
185
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BMCBI
2007
15 years 6 months ago
2007
Background: There is a large amount of microarray data accumulating in public databases, providing various data waiting to be analyzed jointly. Powerful kernel-based methods are c...
157
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BMCBI
2007
15 years 6 months ago
2007
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
153
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BMCBI
2007
15 years 6 months ago
2007
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...