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» New Directions on Agile Methods: A Comparative Analysis
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WSC
1997
15 years 7 months ago
New Development of Optimal Computing Budget Allocation for Discrete Event Simulation
This paper deals with ranking and selection problem via simulation. We present an optimal computing budget allocation technique which can select the best of k simulated designs. T...
Hsiao-Chang Chen, Chun-Hung Chen, Liyi Dai, Enver ...
BMCBI
2004
150views more  BMCBI 2004»
15 years 6 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
BMEI
2008
IEEE
16 years 23 days ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang
ESCIENCE
2006
IEEE
16 years 10 days ago
Hybrid Particle Guide Selection Methods in Multi-Objective Particle Swarm Optimization
This paper presents quantitative comparison of the performance of different methods for selecting the guide particle for multi-objective particle swarm optimization (MOPSO). Two p...
David Ireland, Andrew Lewis, Sanaz Mostaghim, Junw...
BMCBI
2007
92views more  BMCBI 2007»
15 years 6 months ago
Nanopore current transduction analysis of protein binding to non-terminal and terminal DNA regions: analysis of transcription fa
Background: Synthetic transcription factors (STFs) promise to offer a powerful new therapeutic against Cancer, AIDS, and genetic disease. Currently, 10% of drugs are of this type,...
Stephen Winters-Hilt, Amanda Davis, Iftekhar Amin,...