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ICCD
1995
IEEE
109views Hardware» more  ICCD 1995»
15 years 10 months ago
Verifying the performance of the PCI local bus using symbolic techniques
Symbolic model checking is a successful technique for checking properties of large finite-state systems. This method has been used to verify a number of real-world hardware desig...
Sérgio Vale Aguiar Campos, Edmund M. Clarke...
DLOG
2004
15 years 8 months ago
Towards Explaining Semantic Matching
Interoperability among systems using different term vocabularies requires mappings between them. Matching applications generate these mappings. When the matching process utilizes ...
Deborah L. McGuinness, Pavel Shvaiko, Fausto Giunc...
BMCBI
2010
154views more  BMCBI 2010»
15 years 6 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
BMCBI
2007
104views more  BMCBI 2007»
15 years 6 months ago
Predicting active site residue annotations in the Pfam database
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
Jaina Mistry, Alex Bateman, Robert D. Finn
BMCBI
2008
84views more  BMCBI 2008»
15 years 6 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....