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BMCBI
2008
129views more  BMCBI 2008»
15 years 6 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2007
247views more  BMCBI 2007»
15 years 6 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
IMCS
2007
77views more  IMCS 2007»
15 years 6 months ago
Incident response requirements for distributed security information management systems
Purpose – Security information management systems (SIMs) have been providing a unified distributed platform for the efficient management of security information produced by co...
Sarandis Mitropoulos, Dimitrios Patsos, Christos D...
SIGMETRICS
2002
ACM
15 years 6 months ago
Full-system timing-first simulation
Computer system designers often evaluate future design alternatives with detailed simulators that strive for functional fidelity (to execute relevant workloads) and performance fi...
Carl J. Mauer, Mark D. Hill, David A. Wood