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BMCBI
2007
122views more  BMCBI 2007»
15 years 7 months ago
TAP score: torsion angle propensity normalization applied to local protein structure evaluation
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
Silvio C. E. Tosatto, Roberto Battistutta
BMCBI
2007
83views more  BMCBI 2007»
15 years 7 months ago
Identification of sequence motifs significantly associated with antisense activity
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Kyle A. McQuisten, Andrew S. Peek
BMCBI
2008
149views more  BMCBI 2008»
15 years 7 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
BMCBI
2006
94views more  BMCBI 2006»
15 years 7 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
169views more  BMCBI 2006»
15 years 7 months ago
Machine learning techniques in disease forecasting: a case study on rice blast prediction
Background: Diverse modeling approaches viz. neural networks and multiple regression have been followed to date for disease prediction in plant populations. However, due to their ...
Rakesh Kaundal, Amar S. Kapoor, Gajendra P. S. Rag...
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