Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
The collection of multiple genome-scale datasets is now routine, and the frontier of research in systems biology has shifted accordingly. Rather than clustering a single dataset t...
Balaji S. Srinivasan, Nigam H. Shah, Jason Flannic...
Components in a decentralised system are faced with uncertainty as how to best adapt to a changing environment to maintain or optimise system performance. How can individual compo...
The communication mechanism used by the biological cells of higher animals is an integral part of an organisms ability to tolerate cell deficiency or loss. The massive redundancy ...
—Models of regulatory networks become more difficult to construct and understand as they grow in size and complexity. Large models are usually built up from smaller models, repre...
Ranjit Randhawa, Clifford A. Shaffer, John J. Tyso...