The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
This paper promotes compositional reasoning in the context of safety-critical systems, and demonstrates a safety-oriented component model using an application from the automotive ...
— Following a toxic contaminant release, either accidental or intentional, predicting the transport and dispersion of the contaminant becomes a critical problem for Homeland Defe...
Sue Ellen Haupt, George S. Young, Christopher T. A...