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» Modelling Contexts in the Or-BAC Model
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BMCBI
2006
133views more  BMCBI 2006»
15 years 6 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2007
164views more  BMCBI 2007»
15 years 6 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...
ENTCS
2007
97views more  ENTCS 2007»
15 years 6 months ago
Safety-Oriented Design of Component Assemblies using Safety Interfaces
This paper promotes compositional reasoning in the context of safety-critical systems, and demonstrates a safety-oriented component model using an application from the automotive ...
Jonas Elmqvist, Simin Nadjm-Tehrani
JCP
2007
108views more  JCP 2007»
15 years 6 months ago
A Genetic Algorithm Method to Assimilate Sensor Data for a Toxic Contaminant Release
— Following a toxic contaminant release, either accidental or intentional, predicting the transport and dispersion of the contaminant becomes a critical problem for Homeland Defe...
Sue Ellen Haupt, George S. Young, Christopher T. A...