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BMCBI
2010
95views more  BMCBI 2010»
15 years 6 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Generating samples for association studies based on HapMap data
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
Jing Li, Yixuan Chen
BMCBI
2006
106views more  BMCBI 2006»
15 years 6 months ago
Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
Henrik Bengtsson, Ola Hössjer
IJCSA
2006
91views more  IJCSA 2006»
15 years 6 months ago
Possibilistic Explanation
The philosophy literature has been struggling with the problem of defining causality. There has been extensive discussion about it. Hume taught that talk of causation was metaphys...
Sara Boutouhami, Aïcha Mokhtari
CONSTRAINTS
2007
112views more  CONSTRAINTS 2007»
15 years 6 months ago
Maxx: Test Pattern Optimisation with Local Search Over an Extended Logic
In the ECAD area, the Test Generation (TG) problem consists in finding an input vector test for some possible diagnosis (a set of faults) of a digital circuit. Such tests may have ...
Francisco Azevedo