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CSDA
2007
108views more  CSDA 2007»
15 years 6 months ago
Nonlinear random effects mixture models: Maximum likelihood estimation via the EM algorithm
Nonlinear random effects models with finite mixture structures are used to identify polymorphism in pharmacokinetic/ pharmacodynamic (PK/PD) phenotypes. An EM algorithm for maxim...
Xiaoning Wang, Alan Schumitzky, David Z. D'Argenio
HYBRID
2003
Springer
15 years 11 months ago
On the Causality of Mixed-Signal and Hybrid Models
This paper extends the application of the Cantor metric as a mathematical tool for defining causalities from pure discrete models to mixed-signal and hybrid models. Using the Cant...
Jie Liu, Edward A. Lee
NFM
2011
264views Formal Methods» more  NFM 2011»
15 years 1 months ago
Applying Atomicity and Model Decomposition to a Space Craft System in Event-B
Abstract. Event-B is a formal method for modeling and verifying consistency of systems. In formal methods such as Event-B, refinement is the process of enriching or modifying an a...
Asieh Salehi Fathabadi, Abdolbaghi Rezazadeh, Mich...
CSMR
2000
IEEE
15 years 11 months ago
A Proposal for Supporting Software Evolution in Componentware
In practice, a pure top-down and refinement-based development process is not applicable. A more iterative and incremental approach is usually applied with respect to changing req...
Andreas Rausch
ER
2001
Springer
107views Database» more  ER 2001»
15 years 11 months ago
Source Description-Based Approach for the Modeling of Spatial Information Integration
Rapid development of information technology such as mobile terminals and GPS systems enabled information services that provide location-oriented information based on users’ posit...
Yoshiharu Ishikawa, Hiroyuki Kitagawa