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HISB
2011
99views more  HISB 2011»
14 years 5 months ago
Quantitative Modeling the Saccharomyces cerevisiae FLR1 Regulatory Network Using an S-System Formalism
—We address the problem of finding a mathematical model for the genetic network regulating the stress response of the yeast Saccharomyces cerevisiae to the fungicide mancozeb. A...
Dulce Calçada, Susana Vinga, Ana T. Freitas...
HYBRID
2007
Springer
16 years 13 days ago
Switch Detection in Genetic Regulatory Networks
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Riccardo Porreca, Giancarlo Ferrari-Trecate, Danie...
NN
2010
Springer
189views Neural Networks» more  NN 2010»
15 years 1 months ago
Sparse kernel learning with LASSO and Bayesian inference algorithm
Kernelized LASSO (Least Absolute Selection and Shrinkage Operator) has been investigated in two separate recent papers (Gao et al., 2008) and (Wang et al., 2007). This paper is co...
Junbin Gao, Paul W. Kwan, Daming Shi
IJBRA
2006
59views more  IJBRA 2006»
15 years 6 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
BMCBI
2004
323views more  BMCBI 2004»
15 years 6 months ago
Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...