—We address the problem of finding a mathematical model for the genetic network regulating the stress response of the yeast Saccharomyces cerevisiae to the fungicide mancozeb. A...
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Kernelized LASSO (Least Absolute Selection and Shrinkage Operator) has been investigated in two separate recent papers (Gao et al., 2008) and (Wang et al., 2007). This paper is co...
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...