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174
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BMCBI
2010
2010
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
15 years 6 months ago
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
148
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BMCBI
2007
15 years 6 months ago
2007
Background: Clustering is an important analysis performed on microarray gene expression data since it groups genes which have similar expression patterns and enables the explorati...
178
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BMCBI
2007
15 years 6 months ago
2007
Background: In proteomics experiments, database-search programs are the method of choice for protein identification from tandem mass spectra. As amino acid sequence databases grow...
175
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BMCBI
2008
15 years 6 months ago
2008
Background: The recent emergence of high-throughput automated image acquisition technologies has forever changed how cell biologists collect and analyze data. Historically, the in...
174
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BMCBI
2008
15 years 6 months ago
2008
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...