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BMCBI
2008
139views more  BMCBI 2008»
15 years 6 months ago
A topological transformation in evolutionary tree search methods based on maximum likelihood combining p-ECR and neighbor joinin
Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
Maozu Guo, Jian-Fu Li, Yang Liu
BMCBI
2011
14 years 10 months ago
A fast and accurate method to detect allelic genomic imbalances underlying mosaic rearrangements using SNP array data
Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal pop...
Juan R. González, Benjamin Rodriguez-Santia...
BMCBI
2010
99views more  BMCBI 2010»
15 years 6 months ago
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
Hailong Meng, Andrew R. Joyce, Daniel E. Adkins, P...
FIMH
2003
Springer
15 years 12 months ago
A Levelset Based Method for Segmenting the Heart in 3D+T Gated SPECT Images
Keywords Levelset methods were introduced in medical images segmentation by Malladi et al in 1995. In this paper, we propose several improvements of the original method to speed u...
Arnaud Charnoz, Diane Lingrand, Johan Montagnat
SDM
2012
SIAM
234views Data Mining» more  SDM 2012»
13 years 9 months ago
On Evaluation of Outlier Rankings and Outlier Scores
Outlier detection research is currently focusing on the development of new methods and on improving the computation time for these methods. Evaluation however is rather heuristic,...
Erich Schubert, Remigius Wojdanowski, Arthur Zimek...