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BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2010
121views more  BMCBI 2010»
15 years 6 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
ISBI
2008
IEEE
16 years 1 months ago
Comparative assessment of different energy mapping methods for generation of 511-keV attenuation map from CT images in PET/CT sy
The use of X-ray CT images for CT-based attenuation correction (CTAC) of PET data results in the decrease of overall scanning time and creates a noise-free attenuation map (μmap)...
Maryam Shirmohammad, Mohammad Reza Ay, Saeed Sarka...
CSB
2004
IEEE
131views Bioinformatics» more  CSB 2004»
15 years 10 months ago
Improved Fourier Transform Method for Unsupervised Cell-Cycle Regulated Gene Prediction
Motivation: Cell-cycle regulated gene prediction using microarray time-course measurements of the mRNA expression levels of genes has been used by several researchers. The popular...
Karuturi R. Krishna Murthy, Liu Jian Hua
BMCBI
2010
98views more  BMCBI 2010»
15 years 6 months ago
An optimized TOPS+ comparison method for enhanced TOPS models
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
Mallika Veeramalai, David Gilbert, Gabriel Valient...