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AAAI
1998
15 years 7 months ago
Fast Probabilistic Modeling for Combinatorial Optimization
Probabilistic models have recently been utilized for the optimization of large combinatorial search problems. However, complex probabilistic models that attempt to capture interpa...
Shumeet Baluja, Scott Davies
BMCBI
2010
133views more  BMCBI 2010»
15 years 6 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2008
91views more  BMCBI 2008»
15 years 6 months ago
t2prhd: a tool to study the patterns of repeat evolution
Background: The models developed to characterize the evolution of multigene families (such as the birth-and-death and the concerted models) have also been applied on the level of ...
Botond Sipos, Kálmán Somogyi, Istv&a...
BMCBI
2008
83views more  BMCBI 2008»
15 years 6 months ago
Terminologies for text-mining; an experiment in the lipoprotein metabolism domain
Background: The engineering of ontologies, especially with a view to a text-mining use, is still a new research field. There does not yet exist a well-defined theory and technolog...
Dimitra Alexopoulou, Thomas Wächter, Laura Pi...
BMCBI
2006
127views more  BMCBI 2006»
15 years 6 months ago
On the attenuation and amplification of molecular noise in genetic regulatory networks
Background: Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanis...
Bor-Sen Chen, Yu-Chao Wang