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ICCS
1997
Springer
15 years 10 months ago
Uncovering the Conceptual Models in Ripple Down Rules
: The need for analysis and modeling of knowledge has been espoused by many researchers as a prerequisite to building knowledge based systems (KBS). This approach has done little t...
Debbie Richards, Paul Compton
BMCBI
2010
148views more  BMCBI 2010»
15 years 6 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
BMCBI
2010
170views more  BMCBI 2010»
15 years 6 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2010
202views more  BMCBI 2010»
15 years 6 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
BMCBI
2008
140views more  BMCBI 2008»
15 years 6 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh