5234 search results - page 635 / 1047 » Method Components - Rationale Revealed |
204
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BMCBI
2010
15 years 7 months ago
2010
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
220
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BMCBI
2007
15 years 7 months ago
2007
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...
195
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BMCBI
2010
15 years 7 months ago
2010
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
190
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BMCBI
2010
15 years 7 months ago
2010
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
234
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BMCBI
2008
15 years 7 months ago
2008
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...